Cytokinesis series Midbodies and phragmoplasts: analogous structures involved in cytokinesis
نویسندگان
چکیده
University of Wisconsin-Madison, Department of Botany, 430 Lincoln Dr., Madison, WI 53706, USA University of La Plata-CONICET, Argentina, P.O. Box 327, 1900, La Plata, Argentina University of Wisconsin-Madison, Laboratory of Molecular Biology, 1425 Linden Dr., Madison, WI 53706, USA University of Wisconsin-Madison, Department of Genetics and Medical Genetics, 425-G Henry Mall, Madison, WI 53706, USA
منابع مشابه
Midbodies and phragmoplasts: analogous structures involved in cytokinesis.
Cytokinesis is an event common to all organisms that involves the precise coordination of independent pathways involved in cell-cycle regulation and microtubule, membrane, actin and organelle dynamics. In animal cells, the spindle midzone/midbody with associated endo-membrane system are required for late cytokinesis events, including furrow ingression and scission. In plants, cytokinesis is med...
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BACKGROUND The midbody is a transient complex structure containing proteins involved in cytokinesis. Up to now, it has been described only in Metazoa. Other eukaryotes present a variety of structures implied in the last steps of cell division, such as the septum in fungi or the phragmoplast in plants. However, it is unclear whether these structures are homologous (derive from a common ancestral...
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Cytokinesis is the final stage in cell division. Although integrins can regulate cytokinesis, the mechanisms involved are not fully understood. In this study, we demonstrate that integrin-regulated ERK (extracellular signal-related kinase) and RSK (p90 ribosomal S6 kinase) signaling promotes successful cytokinesis. Inhibiting the activation of ERK and RSK in CHO cells by a mutation in the integ...
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TSG101 and ALIX both function in HIV budding and in vesicle formation at the multivesicular body (MVB), where they interact with other Endosomal Sorting Complex Required for Transport (ESCRT) pathway factors required for release of viruses and vesicles. Proteomic analyses revealed that ALIX and TSG101/ESCRT-I also bind a series of proteins involved in cytokinesis, including CEP55, CD2AP, ROCK1,...
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